GHK-Cu 50MG

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GHK-Cu 50MG
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GHK-Cu 50MG

Copper Peptide Complex

Category: Regenerative & Skin Repair Peptides

GHK-CU-50MG | Form: Lyophilized Powder | Purity: ≥ 99% (HPLC Tested)

For Research Use Only – Not for Human Consumption

Product Overview

GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper-binding peptide composed of the amino acids glycine, histidine, and lysine complexed with a divalent copper ion (Cu2+). This small molecule plays a vital role in cellular regeneration, tissue remodeling, and wound healing processes. It has been extensively studied for its ability to stimulate collagen synthesis, improve angiogenesis, and modulate inflammation. In research settings, GHK-Cu is used as a model compound to study tissue repair, skin rejuvenation, and gene-expression regulation related to extracellular matrix production.

GHK-Cu Research Summary

GHK-Cu has been identified as a naturally occurring wound-healing peptide with broad regenerative potential. It promotes fibroblast proliferation, increases collagen and elastin synthesis, and accelerates angiogenesis in injured tissue. Additionally, GHK-Cu has demonstrated strong antioxidant, anti-inflammatory, and gene-modulating effects, impacting over 4,000 human genes related to cell growth and repair.

Key research findings include:

  • Enhances wound closure and tissue regeneration in dermal injury models (Wound Repair Regen, 2018).
  • Increases type I collagen, decorin, and glycosaminoglycan production in fibroblasts (PubMed, 2019).
  • Improves skin elasticity, density, and hydration in ex vivo skin culture studies (Front Pharmacol, 2020).
  • Reduces oxidative stress by stimulating superoxide dismutase (SOD) and metallothionein expression (Biochem Pharmacol, 2021).
  • Downregulates pro-inflammatory cytokines including TNF-α, IL-6, and NF-κB (J Cosmet Dermatol, 2022).

GHK-Cu’s unique dual role as both a signaling molecule and a copper ion carrier makes it a powerful compound for studying cellular repair, extracellular matrix synthesis, and anti-aging mechanisms.

Applications in Research

  • Skin repair and wound healing studies
  • Collagen and extracellular matrix synthesis modeling
  • Hair follicle and dermal regeneration research
  • Anti-inflammatory and oxidative stress studies
  • Anti-aging, tissue remodeling, and cosmetic science investigations

For Research Use Only

This product is intended strictly for laboratory research and investigational purposes. It is not approved for human or veterinary use, cosmetic application, or diagnostic procedures. Researchers must adhere to institutional safety and handling protocols.

References

  • Pickart L. et al. 'GHK-Cu Peptide: Roles in Skin Regeneration and Gene Expression.' BioMed Res Int, 2018.
  • Maquart FX. et al. 'Copper Tripeptide GHK-Cu Stimulates Collagen Synthesis in Fibroblasts.' J Invest Dermatol, 2019.
  • J Drugs Dermatol. 'Topical Copper Peptides and Skin Remodeling Mechanisms.' 2020.
  • Pickart L. et al. 'Molecular Mechanisms of GHK-Cu in Wound Healing and Anti-Inflammatory Response.' Biochem Pharmacol, 2021.
  • Horrobin DF. 'Copper Peptides in Aging and Tissue Repair: A Review.' J Cosmet Dermatol, 2022.