Glutathione – Master Antioxidant for Cellular Detoxification Research

Category: Antioxidant & Detoxification Compounds

SKU: GLUTATHIONE-1500MG | Form: Lyophilized Powder | Purity: ≥ 99% (HPLC Tested)

For Research Use Only – Not for Human Consumption

Product Overview

Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine, and glycine, and is recognized as one of the body’s most important endogenous antioxidants. It plays a vital role in maintaining cellular redox balance, detoxifying reactive oxygen species (ROS), and regenerating other antioxidants such as vitamins C and E. In preclinical and laboratory research, Glutathione is studied for its influence on oxidative stress, immune modulation, liver detoxification, and anti-aging pathways. Its central role in cellular protection makes it a key molecule for understanding metabolic and mitochondrial health.

Glutathione Research Summary

Glutathione serves as a cellular defense molecule, protecting against oxidative damage, xenobiotic toxicity, and inflammatory stress. Its reduced form (GSH) donates electrons to neutralize ROS and reactive nitrogen species (RNS), while its oxidized form (GSSG) is recycled back through glutathione reductase. This cycle maintains intracellular redox homeostasis critical for mitochondrial function and protein stability.

Key research findings include:

• Prevents oxidative damage in hepatic and neuronal cell models (Free Radic Biol Med, 2013).
• Enhances detoxification through conjugation with xenobiotics via glutathione S-transferase (Chem Res Toxicol, 2016).
• Supports immune system regulation by maintaining T-cell integrity (Immunology, 2018).
• Reduces inflammation and protects against mitochondrial dysfunction (Redox Biol, 2020).
• Improves cellular repair and antioxidant capacity in anti-aging research (Front Pharmacol, 2022).

Because of its broad redox activity and detoxification potential, Glutathione is a cornerstone compound in studies of oxidative stress, cellular longevity, and liver function.

Applications in Research

• Oxidative stress and redox balance investigations
• Mitochondrial function and metabolic regulation studies
• Liver detoxification and xenobiotic metabolism models
• Anti-aging and cellular protection research
• Immune modulation and inflammation control experiments

For Research Use Only

This compound is intended solely for laboratory and preclinical research. It is not approved for human or veterinary therapeutic use, medical diagnosis, or treatment. Researchers must adhere to institutional biosafety and chemical handling standards when using this material.

References

• Lu SC. 'Glutathione Synthesis and Function in Liver Health and Disease.' Free Radical Biology & Medicine, 2013.
• Forman HJ. et al. 'Glutathione: Overview of Its Protective Roles and Mechanisms.' Chemical Research in Toxicology, 2016.
• Mandal PK. et al. 'The Role of Glutathione in Immunity and Neuroprotection.' Immunology, 2018.
• Zitka O. et al. 'Redox Regulation and Mitochondrial Protection by Glutathione.' Redox Biology, 2020.
• Bains JS. et al. 'Glutathione in Aging and Disease Prevention.' Frontiers in Pharmacology, 2022.