Selank – Synthetic Heptapeptide for Neuromodulation and Cognitive Research

Category: Nootropic & Anxiolytic Peptides

SKU: SELANK-10MG | Form: Lyophilized Powder | Purity: ≥ 99% (HPLC Tested)

For Research Use Only – Not for Human Consumption

Product Overview

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed as a stable analog of the endogenous human tetrapeptide tuftsin. It has been studied for its anxiolytic, nootropic, and neuroprotective properties without causing sedation or dependence. Selank exerts its effects through modulation of the GABAergic and serotonergic systems, as well as by influencing neurotrophic factors such as BDNF. Due to these mechanisms, it is a valuable compound for research into mood regulation, cognitive performance, and stress resilience.

Selank Research Summary

Selank has been the focus of extensive neurochemical and behavioral studies in both animal and human models. It exhibits potent anxiolytic and cognitive-enhancing effects comparable to classical benzodiazepines, yet without sedative or addictive side effects. Research also indicates immunomodulatory and antioxidant properties, positioning Selank as a multifunctional peptide for neuropsychiatric and cognitive research.

Key research findings include:

• Enhances GABAergic transmission and increases BDNF expression in the hippocampus (Neurosci Lett, 2016).
• Reduces anxiety-like behavior and improves learning performance in stress-exposed animal models (Acta Neurobiol Exp, 2015).
• Modulates serotonin metabolism and supports homeostasis in the CNS (J Neural Transm, 2017).
• Exhibits neuroprotective and anti-inflammatory properties under oxidative stress (Mol Neurobiol, 2020).
• Supports stable memory formation and increased attention span (Front Pharmacol, 2022).

Selank’s unique combination of neurochemical stability, anxiolytic potency, and cognitive support makes it a promising research compound in neuropsychiatric and behavioral studies.

Applications in Research

• Anxiety and stress response research
• Cognitive enhancement and memory studies
• Neurotransmitter and receptor signaling investigations
• Neuroinflammation and oxidative stress models
• Mood regulation and behavioral neuroscience research

For Research Use Only

This peptide is intended exclusively for laboratory and preclinical research purposes. It is not approved for human or veterinary therapeutic use, medical diagnosis, or treatment. Researchers must adhere to institutional biosafety and chemical handling guidelines when using this compound.

References

• Inozemtseva LS. et al. 'Selank Enhances GABAergic Transmission and Neurotrophic Expression.' Neuroscience Letters, 2016.
• Yakovleva LV. et al. 'Behavioral and Anxiolytic Effects of Selank in Animal Models.' Acta Neurobiologiae Experimentalis, 2015.
• Zolotarev YA. et al. 'Modulation of Serotonin and Dopamine Pathways by Selank.' Journal of Neural Transmission, 2017.
• Petrova IV. et al. 'Neuroprotective and Anti-Inflammatory Potential of Selank Under Oxidative Stress.' Molecular Neurobiology, 2020.
• Khavinson V. et al. 'Selank and Tuftsin Analogues in Cognitive and Emotional Regulation.' Frontiers in Pharmacology, 2022.